Sweat test for cystic fibrosis: Wearable sweat sensor vs. standard laboratory test

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Improved sweat test method for the diagnosis of cystic fibrosis.

We describe a new technique of collecting sweat for measurement of osmolality and sodium concentrations. Eighty two subjects were studied--39 controls and 43 patients with cystic fibrosis. Adequate amounts of sweat were obtained in 81 subjects and sweat was analysed for both osmolality and sodium concentrations in 73 subjects. The 34 controls gave sweat osmolality and sodium values ranging from...

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Sweat testing for cystic fibrosis

Screening of sweat chloride in newborn infants with the Orion Skin Chloride Measuring System and incorporating some procedural innovations is described. The results indicate that while diagnostic screening for cystic fibrosis can be readily undertaken, the test with the chloride ionselective electrode is best left at least to the second day of life or later because of insufficient sweating in v...

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Comparison of Classic Sweat Test and Crystallization Test in Diagnosis of Cystic Fibrosis

OBJECTIVE Sweat chloride measurement is considered a standard diagnostic tool for cystic fibrosis (CF). This study was performed to compare sweat chloride values obtained by quantitative pilocarpine iontophoresis (classic test) with sweat crystallization detected by direct observation of a drop of perspiration under light microscopy in patients with and without CF. METHODS The tests using bot...

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Guidelines for the performance of the sweat test for the diagnosis of cystic fibrosis.

A multidisciplinary group (representing various professional bodies and supported by the Cystic Fibrosis Trust) has developed evidence-based guidelines for the performance of the sweat test in the UK. The guidelines cover patient information, subject suitability, sweat collection, sweat analysis, quality, interpretation of results, and responsibility for testing and training. The guidelines wer...

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Revisiting sweat chloride test results based on recent guidelines for diagnosis of cystic fibrosis

Objectives Recent sweat chloride guidelines published by the Cystic Fibrosis Foundation changed the intermediate sweat chloride concentration range from 40-59 mmol/L to 30-59 mmol/L for age > 6 months. We wanted to know how this new guideline would impact detection of cystic fibrosis among patients who previously had sweat tests done at Texas Children's Hospital. Methods We revisited sweat ch...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2018

ISSN: 1569-1993

DOI: 10.1016/j.jcf.2018.03.005